WHO interim guidance on pregnancy management in the context of Zika virus infection.

Zika virus is a flavivirus that is primarily transmitted by infected Aedes mosquitoes. This vector also transmits dengue and chikungunya viruses and is commonly found in tropical and sub-tropical environments in Africa, the Americas, Asia and the Pacific. Although Zika virus was first identified in humans in 1952, few outbreaks were documented prior to 2015.(1) Human infection can be asymptomatic, and when there are symptoms, these are usually mild and self-limiting. While the usual pattern of human infection has not changed, the recent potential association between Zika virus infection and congenital microcephaly and Guillain-Barré syndrome in some affected areas(2) has escalated this issue to a Public Health Emergency of International Concern.(2-4)